A multitasking innovation.
Acts against the visible signs of aging with clinically proven efficacy.


by age 40, 
skin oxygen levels reduce by up 
to 60%

Oxygen loss is the main reason for the signs of aging

oath™ technology delivers liquid oxygen directly 
to your skin cells

Improve cell repair & turnover, enhance collagen & elastin production

improves microcirculation

Accelerated blood flow by up to 70%, improving the body's natural delivery of oxygen to your skin cells

what does
o2 niacinamide serum
do for my skin?

100% showed improvement

Wrinkles • Hydration • Skin clarity • Skin tone

97% agree

Skin was smoother & softer

94% agree

Skin was more nourished

91% agree

Skin felt healthier • Was less dull & more radiant
Less irritated • Renewed, revitalized, rejuvenated

ingredients that make a difference⁠

the press weigh in

customers agree

the best serum

“I have been using another serum from Skinceuticals for years but this serum is so much better. Definitely the best serum I’ve used.”


holy grail

“I have been using this product morning and night for the past month and I have seen a huge difference in my deep forehead wrinkles. Not to mention, my skin looks plump and glowy.”


miracle serum
for sensitive skin

“This serum is literally one of the best products I’ve used on my skin.”


the perfect

“My skin looked and felt IMMEDIATELY SMOOTHER and bouncier! I love how much brighter and even toned I looked after just 
a few days, and it only got better after the first week! This serum is perfection!”